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Saône-et-Loire (French pronunciation: [sonelwaʁ]; Arpitan: Sona-et-Lêre) is a department in the Bourgogne-Franche-Comté region in France. It is named after the rivers Saône and Loire, between which it lies, in the country's central-eastern part.
Saône-et-Loire is Bourgogne-Franche-Comté's most populous department with a population of 551,493 as of 2019. It is also its southernmost department, as it is situated on the regional border with Auvergne-Rhône-Alpes. Saône-et-Loire's prefecture is Mâcon, with subprefectures in Autun, Chalon-sur-Saône, Charolles and Louhans. Its INSEE and postcode number is 71.

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