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Central Manchester University Hospital NHS Foundation Trust, was a large NHS foundation trust in Manchester, United Kingdom, that was founded in 2009 and merged with University Hospital of South Manchester NHS Foundation Trust in 2017 to form the current Manchester University NHS Foundation Trust.
The trust ran eight hospitals in Manchester and Trafford: Manchester Royal Infirmary, Royal Manchester Children's Hospital, Saint Mary's Hospital, Manchester, Manchester Royal Eye Hospital and University Dental Hospital of Manchester in Manchester, and Trafford General Hospital, Altrincham Hospital and Stretford Memorial Hospital in Trafford.

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