To get a proper comparison you would need to do the same route with the same weather conditions and temperature with the same traffic in exactly the same places travelling at the same speed or...
...hire a wind tunnel.
MIRA charge £900 including vat per hour for their tunnel.
Keeping the maths simple assuming you get 4.0m/kWh without the mudflaps and you pay £0.09 to charge at home it costs £0.0225p/mile
If the mudflaps decrease your m/kWh to 3.9m/kWh your cost per mile increases to £0.0231p/kWh a difference of £0.0006p/kWh
Or put another way you would need to do 15,000,000 miles before the increased cost per mile is equivalent to the hire of the wind tunnel for an hour.